Propoxyphene

Drug Name: Propoxyphene

Drug Abbreviation: PPX

Drug Slang Term(s): Darvon

Drug Screening Cut-off in Urine: 300 ng/mL


Drug Information:

Propoxyphene is a drug often prescribed to treat pain and is related structurally to methadone. Propoxyphene is generally taken orally and its effects peak in 1 - 2 hours. Overdose of propoxyphene effects the brain and can cause severe euphoria. Extended use of propoxyphene can cause respiratory depression, analgesia, stupor, and coma.


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TCA, Tricyclic Antidepressants

Drug Name: Tricyclic Antidepressants

Drug Abbreviation: TCA

Drug Slang Term(s): Vivactil, Anafranil, Janimine, Tofranil


Drug Screening Cut-off in Urine: 1,000 ng/mL


Drug Information:

TCA (Tricyclic Antidepressants) are commonly used for the treatment of depressive disorders. TCA overdoses can result in profound central nervous system depression, cardiotoxicity and anticholinergic effects. TCA overdose is the most common cause of death from prescription drugs. TCAs are taken orally or sometimes by injection. TCAs are metabolized in the liver. Both TCAs and their metabolites are excreted in urine mostly in the form of metabolites for up to ten days.


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